Ten years into his career, William Hagstrom, CEO of Crescendo Bioscience, says he had an epiphany. Working at a billion-dollar company, he remembers leaving a lateral meeting when a colleague approached him and told him to “relax, it’s only a job, it’s not a crusade.” And this comment hit him like a ton of bricks: if he was going to invest his life and time into a venture, it better be a crusade.