Dr. John Adler, Jr. and John “Trip” Adler III discuss their entrepreneurial experience and evolution as a business leader: For Dr. Adler, he describes his bumpy course in developing his biotechnology company, Accuray Incorporated; for his son Trip, he emphasizes the persistence and luck in developing Scribd, a social publishing site. Despite building companies in different fields, the two offer the same central advice necessary in building a successful company: trust yourself, have common sense, and there are no rules.